All Posts Tagged With: "Microbiome"
“RePOOPulate” could help cure C. difficile
Researchers have created a synthetic “poop” aimed at treating recurrent infections of C. difficile, a toxin-producing bacterium that causes severe and often debilitating diarrhea.
The fake stool, dubbed “RePOOPulate,” is intended to replace donated human stool used in fecal transplants, a treatment that’s been successful in overcoming intractable cases of C. difficile infection.
Clostridium difficile can take hold when a person is exposed to the highly contagious bacteria while taking antibiotics for another infection. Because those drugs destroy healthy, protective bacteria in the gut, C. diff is allowed to overpopulate the large intestine.
C. diff is typically treated with a different antibiotic, but can rebound once treatment stops, leading to chronic rounds of re-infection and retreatment. The disease can lead to severe and life-threatening inflammation of the colon.